Player_Defense
| NameFL | TAbb | PosN | T | OppFumR | Sack | SackYds | Int | IntY | IntAvg | IntTDs |
| Kyzir White | CAL | Left I LB | 141 | 1 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Bobby Wagner | SEA | Middle LB | 140 | 3 | 3 | 20 | 3 | 34 | 11.3 | 0 |
| C.J. Mosley | DAL | Middle LB | 131 | 0 | 2 | 18 | 0 | 0 | 0.0 | 0 |
| Roquan Smith | BUF | Left I LB | 127 | 0 | 1 | 10 | 0 | 0 | 0.0 | 0 |
| Tremaine Edmunds | CLE | Middle LB | 126 | 0 | 1 | 8 | 1 | 22 | 22.0 | 0 |
| Myles Jack | BAC | Right I LB | 121 | 1 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Zaire Franklin | BUF | Right LB | 121 | 0 | 0 | 0 | 3 | 67 | 22.3 | 1 |
| De'Vondre Campbell | PHI | Left I LB | 118 | 2 | 1 | 3 | 1 | 12 | 12.0 | 0 |
| Lavonte David | JAC | Left I LB | 117 | 1 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Preston Smith | BAC | Right O LB | 114 | 1 | 2 | 17 | 0 | 0 | 0.0 | 0 |
| Bobby Okereke | LAD | Middle LB | 108 | 1 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Trevon Diggs | LAM | Right CB | 108 | 0 | 0 | 0 | 3 | 10 | 3.3 | 0 |
| Demario Davis | SF4 | Middle LB | 107 | 1 | 1 | 2 | 1 | 4 | 4.0 | 0 |
| Josh Bynes | NYG | Right I LB | 107 | 0 | 0 | 0 | 1 | 4 | 4.0 | 0 |
| Nick Vigil | TTR | Right LB | 107 | 1 | 0 | 0 | 2 | 25 | 12.5 | 0 |
| Josh Allen | LAC | Left O LB | 104 | 2 | 2 | 19 | 0 | 0 | 0.0 | 0 |
| Kaden Elliss | CAL | O LB | 104 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Fred Warner | PHO | Middle LB | 103 | 2 | 1 | 7 | 1 | 0 | 0.0 | 0 |
| Jerome Baker | BUF | Right I LB | 101 | 1 | 2 | 12 | 2 | 26 | 13.0 | 1 |
| Jayon Brown | SCS | I LB | 101 | 2 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Denzel Perryman | LAM | Middle LB | 101 | 4 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Justin Houston | SHR | Right O LB | 100 | 0 | 1 | 6 | 0 | 0 | 0.0 | 0 |
| Jalen Ramsey | SF4 | Left CB | 100 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Denzel Ward | LAC | Right CB | 99 | 0 | 0 | 0 | 2 | 0 | 0.0 | 0 |
| Deion Jones | OAK | Right I LB | 99 | 1 | 0 | 0 | 1 | 10 | 10.0 | 0 |
| Willie Gay | SCS | Left LB | 99 | 2 | 0 | 0 | 1 | 4 | 4.0 | 0 |
| Trevis Gipson | NOV | Left O LB | 98 | 1 | 3 | 25 | 1 | 0 | 0.0 | 0 |
| Anthony Barr | CLE | Left LB | 98 | 2 | 3 | 23 | 1 | 20 | 20.0 | 0 |
| Austin Bryant | NYG | Left O LB | 98 | 1 | 0 | 0 | 2 | 13 | 6.5 | 0 |
| Cole Holcomb | CAL | Right LB | 97 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Anthony Walker | CHI | Middle LB | 96 | 3 | 3 | 26 | 0 | 0 | 0.0 | 0 |
| Markus Golden | DAL | Left O LB | 93 | 1 | 6 | 38 | 2 | 37 | 18.5 | 0 |
| Jeremy Chinn | LAC | Strong Safety | 93 | 1 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Uchenna Nwosu | BAC | Right O LB | 93 | 0 | 0 | 0 | 2 | 32 | 16.0 | 0 |
| Azeez Al-Shaair | SEA | Right LB | 93 | 3 | 0 | 0 | 1 | 0 | 0.0 | 0 |
| Shaquil Barrett | SEA | Left O LB | 92 | 0 | 2 | 14 | 4 | 8 | 2.0 | 0 |
| Jalen Mills | CAL | Right CB | 92 | 1 | 0 | 0 | 3 | 23 | 7.7 | 0 |
| Eric Kendricks | NOS | Middle LB | 92 | 2 | 0 | 0 | 2 | 0 | 0.0 | 0 |
| Von Miller | LAD | Left O LB | 89 | 2 | 8 | 51 | 1 | 0 | 0.0 | 0 |
| Leonard Floyd | PHO | Right O LB | 89 | 2 | 5 | 22 | 1 | 0 | 0.0 | 0 |
| Anthony Nelson | NYG | O LB | 89 | 1 | 0 | 0 | 2 | 25 | 12.5 | 0 |
| Quandre Diggs | LAD | Free Safety | 89 | 1 | 0 | 0 | 3 | 67 | 22.3 | 1 |
| Alex Singleton | NOS | Right LB | 88 | 0 | 1 | 10 | 2 | 0 | 0.0 | 0 |
| Jamel Dean | LAD | Right CB | 88 | 0 | 0 | 0 | 4 | 53 | 13.3 | 0 |
| Darius Slay | SEA | Left CB | 88 | 0 | 0 | 0 | 4 | 63 | 15.8 | 1 |
| Bryce Hall | NYG | Left CB | 88 | 0 | 0 | 0 | 2 | 25 | 12.5 | 0 |
| Zach Cunningham | LAM | Right I LB | 87 | 0 | 2 | 16 | 0 | 0 | 0.0 | 0 |
| Patrick Peterson | LAD | Right CB | 87 | 0 | 0 | 0 | 1 | 0 | 0.0 | 0 |
| Zaven Collins | LAC | LB | 87 | 0 | 0 | 0 | 2 | 45 | 22.5 | 0 |
| Kenny Clark | GBP | Nose Tackle | 86 | 0 | 4 | 23 | 0 | 0 | 0.0 | 0 |
| Rasul Douglas | PHI | Right CB | 86 | 0 | 0 | 0 | 2 | 24 | 12.0 | 0 |
| Darnell Savage | NOV | Free Safety | 86 | 1 | 0 | 0 | 2 | 52 | 26.0 | 1 |
| Mack Wilson | CHI | O LB | 86 | 2 | 0 | 0 | 1 | 4 | 4.0 | 0 |
| Nick Bolton | NOV | Right LB | 85 | 0 | 1 | 5 | 4 | 86 | 21.5 | 1 |
| Chandler Jones | SHR | Right O LB | 84 | 2 | 8 | 64 | 1 | 4 | 4.0 | 0 |
| Logan Wilson | PHI | Right LB | 84 | 2 | 1 | 6 | 1 | 0 | 0.0 | 0 |
| Eric Rowe | NYG | 1st Defensive Back | 84 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| J.C. Jackson | PHI | Left CB | 84 | 0 | 0 | 0 | 2 | 4 | 2.0 | 0 |
| Rashan Gary | LAM | Left O LB | 83 | 1 | 24 | 182 | 1 | 0 | 0.0 | 0 |
| Kendall Fuller | SCS | Right CB | 83 | 0 | 1 | 7 | 1 | 0 | 0.0 | 0 |
| James Bradberry | MIS | Left CB | 82 | 0 | 1 | 5 | 1 | 22 | 22.0 | 0 |
| Jordan Whitehead | DAL | Strong Safety | 82 | 0 | 0 | 0 | 3 | 16 | 5.3 | 0 |
| Kenny Moore II | NOV | CB | 81 | 0 | 0 | 0 | 2 | 20 | 10.0 | 0 |
| Jaylon Johnson | OAK | Right CB | 81 | 0 | 0 | 0 | 2 | 20 | 10.0 | 0 |
| Rock Ya-Sin | CLE | Left CB | 80 | 0 | 2 | 16 | 1 | 10 | 10.0 | 0 |
| Tae Crowder | MIS | Right I LB | 80 | 0 | 2 | 5 | 0 | 0 | 0.0 | 0 |
| Chidobe Awuzie | CLE | Right CB | 80 | 0 | 1 | 12 | 4 | 33 | 8.3 | 0 |
| Jessie Bates | CLE | Free Safety | 80 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Shaq Thompson | OAK | Right LB | 79 | 2 | 2 | 13 | 0 | 0 | 0.0 | 0 |
| Ja'Whaun Bentley | TTR | Left I LB | 78 | 2 | 1 | 6 | 1 | 0 | 0.0 | 0 |
| Marshon Lattimore | PHO | Right CB | 78 | 1 | 0 | 0 | 4 | 64 | 16.0 | 1 |
| Tre'Davious White | BAC | Left CB | 78 | 0 | 0 | 0 | 1 | 20 | 20.0 | 0 |
| Odafe Oweh | MIS | O LB | 77 | 1 | 4 | 36 | 1 | 68 | 68.0 | 1 |
| Kyle Van Noy | JAC | Right O LB | 77 | 1 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Casey Hayward | GBP | Right CB | 77 | 1 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Tyeler Davison | JAC | Nose Tackle | 76 | 2 | 2 | 2 | 0 | 0 | 0.0 | 0 |
| Alex Anzalone | DET | Left I LB | 76 | 1 | 1 | 0 | 1 | 20 | 20.0 | 0 |
| Anthony Harris | CAL | Strong Safety | 76 | 1 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Andrew Van Ginkel | JAC | Right O LB | 76 | 1 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Budda Baker | LAC | Free Safety | 75 | 0 | 2 | 8 | 0 | 0 | 0.0 | 0 |
| A.J. Bouye | TTR | Left CB | 75 | 0 | 0 | 0 | 3 | 49 | 16.3 | 1 |
| Kristian Fulton | DAL | Right CB | 75 | 0 | 0 | 0 | 3 | 14 | 4.7 | 0 |
| Joe Schobert | NOV | Left I LB | 74 | 3 | 1 | 0 | 0 | 0 | 0.0 | 0 |
| Byron Murphy | NYG | Left CB | 74 | 1 | 0 | 0 | 3 | 32 | 10.7 | 0 |
| Jordan Poyer | PHO | Strong Safety | 74 | 0 | 0 | 0 | 1 | 25 | 25.0 | 0 |
| T.J. Watt | PHO | Left O LB | 73 | 1 | 4 | 31 | 1 | 0 | 0.0 | 0 |
| Matt Milano | SF4 | Right LB | 73 | 0 | 2 | 20 | 0 | 0 | 0.0 | 0 |
| Devin McCourty | DET | Free Safety | 73 | 0 | 1 | 4 | 3 | 24 | 8.0 | 0 |
| A.J. Terrell | GBP | Left CB | 73 | 0 | 0 | 0 | 2 | 47 | 23.5 | 0 |
| Bobby McCain | CLE | Free Safety | 73 | 1 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Brandon Williams | SHR | Nose Tackle | 72 | 1 | 3 | 2 | 0 | 0 | 0.0 | 0 |
| Derrek Tuszka | DAL | O LB | 72 | 0 | 1 | 0 | 2 | 22 | 11.0 | 0 |
| Mykal Walker | TTR | I LB | 72 | 0 | 1 | 0 | 1 | 15 | 15.0 | 0 |
| Jaquiski Tartt | MIS | Strong Safety | 72 | 0 | 1 | 10 | 1 | 12 | 12.0 | 0 |
| Derwin James | SHR | Strong Safety | 72 | 0 | 0 | 0 | 1 | 10 | 10.0 | 0 |
| Ashtyn Davis | TTR | Free Safety | 72 | 0 | 0 | 0 | 2 | 25 | 12.5 | 0 |
| Damien Wilson | SHR | Left I LB | 71 | 2 | 3 | 4 | 1 | 0 | 0.0 | 0 |
| J. Owusu-Koramoah | GBP | Right LB | 71 | 0 | 3 | 28 | 1 | 22 | 22.0 | 0 |
| Antoine Winfield Jr. | BAC | Free Safety | 71 | 0 | 1 | 12 | 0 | 0 | 0.0 | 0 |
| Shaquill Griffin | LAC | Left CB | 71 | 0 | 0 | 0 | 1 | 15 | 15.0 | 0 |
| Marcus Williams | LAD | Free Safety | 71 | 1 | 0 | 0 | 2 | 0 | 0.0 | 0 |
| P.J. Williams | LAM | Safety | 71 | 1 | 0 | 0 | 1 | 10 | 10.0 | 0 |
| Byron Jones | SF4 | Right CB | 70 | 0 | 0 | 0 | 2 | 47 | 23.5 | 0 |
| Fabian Moreau | CAL | Right CB | 70 | 2 | 0 | 0 | 1 | 0 | 0.0 | 0 |
| Dean Marlowe | BUF | Strong Safety | 69 | 3 | 0 | 0 | 2 | 40 | 20.0 | 0 |
| Levi Wallace | LAM | Right CB | 69 | 0 | 0 | 0 | 1 | 36 | 36.0 | 1 |
| Greg Newsome II | BUF | Left CB | 69 | 0 | 0 | 0 | 2 | 49 | 24.5 | 1 |
| Cameron Dantzler | BAC | Left CB | 69 | 0 | 0 | 0 | 1 | 25 | 25.0 | 0 |
| Janoris Jenkins | SEA | Left CB | 69 | 0 | 0 | 0 | 2 | 20 | 10.0 | 0 |
| Devin Bush | MIS | Right I LB | 68 | 2 | 4 | 17 | 0 | 0 | 0.0 | 0 |
| Pete Werner | DET | Left LB | 68 | 1 | 1 | 9 | 1 | 20 | 20.0 | 0 |
| Andrew Wingard | OAK | Free Safety | 68 | 0 | 0 | 0 | 3 | 12 | 4.0 | 0 |
| Jalen Thompson | TTR | Strong Safety | 68 | 0 | 0 | 0 | 1 | 15 | 15.0 | 0 |
| Trevon Moehrig | PHI | Free Safety | 68 | 0 | 0 | 0 | 1 | 0 | 0.0 | 0 |
| Greg Gaines | PHI | Nose Tackle | 67 | 2 | 6 | 42 | 0 | 0 | 0.0 | 0 |
| John Johnson III | NOS | Free Safety | 67 | 1 | 2 | 13 | 3 | 37 | 12.3 | 0 |
| Charles Harris | SF4 | Right O LB | 67 | 0 | 2 | 27 | 1 | 20 | 20.0 | 0 |
| Malcolm Smith | MIS | Left LB | 67 | 2 | 1 | 10 | 0 | 0 | 0.0 | 0 |
| Tyrann Mathieu | SCS | Strong Safety | 67 | 0 | 0 | 0 | 3 | 113 | 37.7 | 2 |
| Adoree' Jackson | CHI | Right CB | 67 | 0 | 0 | 0 | 4 | 33 | 8.3 | 0 |
| Xavien Howard | JAC | Left CB | 67 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Anthony Brown | NOS | Left CB | 67 | 0 | 0 | 0 | 3 | 93 | 31.0 | 1 |
| Kindle Vildor | MIS | Left CB | 67 | 0 | 0 | 0 | 1 | 20 | 20.0 | 0 |
| Jaelan Phillips | CLE | Left O LB | 66 | 0 | 6 | 31 | 0 | 0 | 0.0 | 0 |
| Corey Peters | OAK | Nose Tackle | 66 | 0 | 3 | 22 | 0 | 0 | 0.0 | 0 |
| Rashad Fenton | PHO | Right CB | 66 | 1 | 1 | 6 | 1 | 0 | 0.0 | 0 |
| Jamin Davis | GBP | Middle LB | 66 | 1 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Jermaine Carter | DET | Middle LB | 66 | 0 | 0 | 0 | 1 | 41 | 41.0 | 1 |
| Taylor Rapp | GBP | Free Safety | 66 | 0 | 0 | 0 | 1 | 0 | 0.0 | 0 |
| L'Jarius Sneed | NOV | CB | 65 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Jonathan Allen | SF4 | Right Tackle | 64 | 1 | 8 | 49 | 0 | 0 | 0.0 | 0 |
| Haason Reddick | LAC | Left LB | 64 | 1 | 6 | 53 | 1 | 4 | 4.0 | 0 |
| Jason Pierre-Paul | PHI | Right O LB | 64 | 0 | 0 | 0 | 1 | 4 | 4.0 | 0 |
| Harrison Smith | NOS | Strong Safety | 64 | 1 | 0 | 0 | 6 | 124 | 20.7 | 1 |
| Robert Quinn | OAK | Right O LB | 63 | 1 | 10 | 93 | 2 | 25 | 12.5 | 0 |
| A.J. Klein | NOS | Left LB | 63 | 0 | 3 | 16 | 1 | 12 | 12.0 | 0 |
| Steven Nelson | BUF | Right CB | 63 | 0 | 0 | 0 | 4 | 22 | 5.5 | 0 |
| Kenny Young | SHR | Left I LB | 63 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Dont'a Hightower | SF4 | Right I LB | 63 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Harold Landry | DET | Left O LB | 62 | 0 | 5 | 23 | 0 | 0 | 0.0 | 0 |
| Ernest Jones | GBP | Left I LB | 62 | 0 | 1 | 0 | 0 | 0 | 0.0 | 0 |
| Asante Samuel Jr. | TTR | Left CB | 62 | 0 | 0 | 0 | 5 | 80 | 16.0 | 1 |
| Adrian Amos | NYG | Strong Safety | 62 | 0 | 0 | 0 | 2 | 32 | 16.0 | 0 |
| Terrance Mitchell | SHR | Left CB | 62 | 1 | 0 | 0 | 4 | 53 | 13.3 | 0 |
| Pernell McPhee | LAD | O LB | 60 | 0 | 2 | 22 | 0 | 0 | 0.0 | 0 |
| William Jackson III | OAK | Left CB | 60 | 0 | 2 | 16 | 3 | 16 | 5.3 | 0 |
| Jordan Hicks | PHI | Right I LB | 60 | 0 | 1 | 7 | 0 | 0 | 0.0 | 0 |
| Carlton Davis | DET | Left CB | 60 | 1 | 1 | 3 | 0 | 0 | 0.0 | 0 |
| D.J. Reed | JAC | Right CB | 60 | 0 | 0 | 0 | 5 | 107 | 21.4 | 1 |
| Kwon Alexander | TTR | Right LB | 60 | 0 | 0 | 0 | 1 | 57 | 57.0 | 1 |
| Jordan Fuller | DAL | Strong Safety | 60 | 0 | 0 | 0 | 6 | 16 | 2.7 | 0 |
| DeForest Buckner | LAM | Left Tackle | 59 | 0 | 9 | 59 | 0 | 0 | 0.0 | 0 |
| Donte Jackson | DAL | Right CB | 59 | 0 | 1 | 4 | 2 | 4 | 2.0 | 0 |
| Xavier McKinney | SEA | Free Safety | 59 | 0 | 0 | 0 | 1 | 13 | 13.0 | 0 |
| Jerry Jacobs | SCS | Right CB | 59 | 0 | 0 | 0 | 4 | 58 | 14.5 | 0 |
| Mike Edwards | SF4 | Safety | 58 | 1 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Eli Apple | SHR | Left CB | 58 | 0 | 0 | 0 | 3 | 34 | 11.3 | 0 |
| Mike Purcell | DET | Nose Tackle | 58 | 1 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Damontae Kazee | SF4 | Free Safety | 58 | 0 | 0 | 0 | 6 | 45 | 7.5 | 0 |
| Rodney McLeod | CAL | Free Safety | 57 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Germaine Pratt | NYG | Middle LB | 56 | 0 | 1 | 0 | 0 | 0 | 0.0 | 0 |
| Jayron Kearse | DET | Strong Safety | 56 | 0 | 1 | 10 | 3 | 34 | 11.3 | 0 |
| Erik Harris | BAC | Strong Safety | 56 | 1 | 0 | 0 | 4 | 71 | 17.8 | 1 |
| Chris Jones | LAD | Right Tackle | 55 | 0 | 12 | 67 | 0 | 0 | 0.0 | 0 |
| DaQuan Jones | NOS | Right Tackle | 55 | 0 | 2 | 12 | 0 | 0 | 0.0 | 0 |
| Pat Surtain II | DET | Left CB | 55 | 0 | 1 | 6 | 6 | 38 | 6.3 | 0 |
| Joe Haden | CHI | Left CB | 55 | 1 | 0 | 0 | 3 | 45 | 15.0 | 0 |
| Vita Vea | TTR | Nose Tackle | 54 | 0 | 1 | 0 | 0 | 0 | 0.0 | 0 |
| Amani Hooker | JAC | Strong Safety | 54 | 0 | 0 | 0 | 1 | 20 | 20.0 | 0 |
| Foyesade Oluokun | JAC | Left I LB | 54 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Arik Armstead | DAL | Left Tackle | 53 | 0 | 7 | 58 | 0 | 0 | 0.0 | 0 |
| Minkah Fitzpatrick | MIS | Free Safety | 53 | 0 | 2 | 13 | 2 | 26 | 13.0 | 0 |
| D.J. Reader | BAC | Left Tackle | 53 | 0 | 2 | 0 | 0 | 0 | 0.0 | 0 |
| Lorenzo Carter | GBP | Right O LB | 53 | 1 | 2 | 19 | 0 | 0 | 0.0 | 0 |
| Ed Oliver | NYG | Left Tackle | 53 | 0 | 2 | 14 | 0 | 0 | 0.0 | 0 |
| Xavier Woods | SCS | Free Safety | 53 | 1 | 1 | 8 | 2 | 0 | 0.0 | 0 |
| T.J. Edwards | NOS | Middle LB | 53 | 0 | 1 | 9 | 0 | 0 | 0.0 | 0 |
| Al Woods | LAC | Left Tackle | 52 | 0 | 3 | 30 | 0 | 0 | 0.0 | 0 |
| Raekwon Davis | MIS | Nose Tackle | 52 | 0 | 2 | 20 | 0 | 0 | 0.0 | 0 |
| Leighton Vander Esch | SCS | Right LB | 52 | 0 | 0 | 0 | 1 | 12 | 12.0 | 0 |
| Vonn Bell | LAM | Strong Safety | 51 | 0 | 15 | 112 | 3 | 40 | 13.3 | 0 |
| Tyus Bowser | LAM | Left O LB | 51 | 4 | 10 | 49 | 0 | 0 | 0.0 | 0 |
| Kamren Curl | CHI | Strong Safety | 51 | 0 | 0 | 0 | 4 | 39 | 9.8 | 0 |
| Amani Oruwariye | NOS | Left CB | 51 | 1 | 0 | 0 | 4 | 10 | 2.5 | 0 |
| Quinnen Williams | SCS | Right Tackle | 50 | 1 | 3 | 16 | 0 | 0 | 0.0 | 0 |
| Isaiah Simmons | OAK | Left I LB | 50 | 0 | 2 | 13 | 0 | 0 | 0.0 | 0 |
| Darius Leonard | CHI | Left LB | 50 | 1 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Jevon Holland | BUF | Free Safety | 49 | 0 | 0 | 0 | 2 | 15 | 7.5 | 0 |
| Micah Hyde | SEA | Free Safety | 48 | 0 | 5 | 32 | 2 | 20 | 10.0 | 0 |
| John Franklin-Myers | SCS | Left End | 48 | 0 | 1 | 10 | 0 | 0 | 0.0 | 0 |
| Malik McDowell | BUF | Right Tackle | 46 | 0 | 1 | 8 | 0 | 0 | 0.0 | 0 |
| M.J. Stewart | JAC | Free Safety | 46 | 0 | 0 | 0 | 2 | 0 | 0.0 | 0 |
| Fletcher Cox | LAC | Right Tackle | 45 | 0 | 7 | 39 | 0 | 0 | 0.0 | 0 |
| Adrian Phillips | PHO | Strong Safety | 43 | 1 | 1 | 5 | 4 | 20 | 5.0 | 0 |
| Sam Hubbard | MIS | Left End | 42 | 0 | 8 | 59 | 1 | 0 | 0.0 | 0 |
| Jarran Reed | CLE | Left Tackle | 42 | 1 | 4 | 14 | 0 | 0 | 0.0 | 0 |
| William Gholston | BUF | Right End | 42 | 0 | 1 | 11 | 1 | 20 | 20.0 | 1 |
| Justin Simmons | CHI | Free Safety | 42 | 0 | 1 | 3 | 8 | 87 | 10.9 | 0 |
| D.J. Jones | SEA | Right Tackle | 41 | 0 | 2 | 19 | 0 | 0 | 0.0 | 0 |
| Jimmie Ward | GBP | Free Safety | 39 | 0 | 2 | 15 | 4 | 60 | 15.0 | 0 |
| Nick Bosa | CLE | Left End | 38 | 0 | 6 | 47 | 0 | 0 | 0.0 | 0 |
| Larry Ogunjobi | CHI | Right Tackle | 38 | 0 | 4 | 20 | 0 | 0 | 0.0 | 0 |
| Chris Wormley | PHO | Left End | 38 | 1 | 4 | 31 | 0 | 0 | 0.0 | 0 |
| James Smith-Williams | TTR | Def End | 38 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Trey Hendrickson | OAK | Right End | 37 | 1 | 12 | 95 | 1 | 22 | 22.0 | 0 |
| Shy Tuttle | NOV | Left Tackle | 37 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Christian Ringo | SCS | Def Tackle | 35 | 1 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Marquise Copeland | BUF | Def Tackle | 35 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Matt Judon | NOS | Left O LB | 34 | 0 | 14 | 95 | 0 | 0 | 0.0 | 0 |
| Azeez Ojulari | LAM | Left O LB | 34 | 0 | 8 | 61 | 0 | 0 | 0.0 | 0 |
| Cameron Jordan | DET | Left End | 34 | 1 | 5 | 31 | 0 | 0 | 0.0 | 0 |
| Sean Chandler | NOV | Free Safety | 34 | 0 | 0 | 0 | 6 | 114 | 19.0 | 1 |
| Dalvin Tomlinson | SEA | Left Tackle | 33 | 0 | 3 | 24 | 0 | 0 | 0.0 | 0 |
| Myles Garrett | CLE | Right End | 32 | 0 | 8 | 61 | 0 | 0 | 0.0 | 0 |
| Montez Sweat | LAM | Right End | 32 | 1 | 5 | 36 | 1 | 4 | 4.0 | 0 |
| DeMarcus Lawrence | JAC | Left End | 32 | 0 | 2 | 20 | 0 | 0 | 0.0 | 0 |
| Kevin Byard | OAK | Free Safety | 32 | 0 | 0 | 0 | 3 | 20 | 6.7 | 0 |
| Zach Allen | SHR | Right End | 31 | 1 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Christian Wilkins | JAC | Left End | 31 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Jonathan Greenard | SEA | Right End | 30 | 0 | 7 | 41 | 0 | 0 | 0.0 | 0 |
| Denico Autry | NOS | Left End | 30 | 0 | 5 | 34 | 0 | 0 | 0.0 | 0 |
| Jake Martin | CAL | Left End | 30 | 1 | 3 | 20 | 0 | 0 | 0.0 | 0 |
| Michael Pierce | CHI | Right Tackle | 29 | 0 | 1 | 9 | 0 | 0 | 0.0 | 0 |
| Marcus Davenport | CHI | Right End | 28 | 0 | 6 | 41 | 1 | 0 | 0.0 | 0 |
| Jerry Hughes | SHR | Right End | 28 | 0 | 3 | 19 | 1 | 12 | 12.0 | 0 |
| Grover Stewart | LAD | Right Tackle | 28 | 0 | 2 | 8 | 0 | 0 | 0.0 | 0 |
| Eddie Jackson | SHR | Free Safety | 28 | 0 | 1 | 5 | 0 | 0 | 0.0 | 0 |
| Deatrich Wise Jr | PHI | Right End | 27 | 0 | 2 | 15 | 0 | 0 | 0.0 | 0 |
| Leonard Williams | CHI | Right End | 27 | 1 | 1 | 13 | 0 | 0 | 0.0 | 0 |
| David Onyemata | BAC | Right Tackle | 27 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Malik Hooker | PHI | Strong Safety | 26 | 0 | 1 | 5 | 3 | 24 | 8.0 | 0 |
| Sheldon Richardson | NOV | Def Tackle | 26 | 0 | 1 | 8 | 0 | 0 | 0.0 | 0 |
| Folorunso Fatukasi | PHO | Left Tackle | 26 | 1 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Poona Ford | CLE | Right Tackle | 26 | 1 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Yannick Ngakoue | DAL | Right End | 25 | 0 | 6 | 34 | 0 | 0 | 0.0 | 0 |
| Grady Jarrett | NOV | Right End | 25 | 0 | 1 | 10 | 0 | 0 | 0.0 | 0 |
| Micah Parsons | OAK | Left LB | 24 | 0 | 6 | 48 | 0 | 0 | 0.0 | 0 |
| Joey Bosa | PHI | Left O LB | 24 | 0 | 6 | 49 | 2 | 12 | 6.0 | 0 |
| Jadeveon Clowney | MIS | Left End | 24 | 0 | 5 | 38 | 1 | 0 | 0.0 | 0 |
| Darrell Taylor | BAC | Left End | 24 | 0 | 4 | 32 | 1 | 89 | 89.0 | 1 |
| Harrison Phillips | DAL | Right Tackle | 24 | 0 | 3 | 27 | 0 | 0 | 0.0 | 0 |
| Greg Rousseau | NOV | Left End | 24 | 0 | 2 | 9 | 0 | 0 | 0.0 | 0 |
| Maxx Crosby | TTR | Left End | 24 | 0 | 1 | 3 | 1 | 0 | 0.0 | 0 |
| Akiem Hicks | BUF | Left End | 23 | 1 | 2 | 9 | 0 | 0 | 0.0 | 0 |
| A'Shawn Robinson | LAD | Left End | 23 | 0 | 0 | 0 | 1 | 0 | 0.0 | 0 |
| Brian Burns | DAL | Left End | 22 | 0 | 6 | 55 | 0 | 0 | 0.0 | 0 |
| Emmanuel Ogbah | GBP | Def End | 22 | 0 | 3 | 18 | 0 | 0 | 0.0 | 0 |
| Dean Lowry | NYG | Left End | 22 | 0 | 2 | 18 | 0 | 0 | 0.0 | 0 |
| Rasheem Green | LAC | Right End | 22 | 0 | 1 | 11 | 0 | 0 | 0.0 | 0 |
| Maliek Collins | PHO | Right Tackle | 21 | 1 | 5 | 27 | 0 | 0 | 0.0 | 0 |
| Jeffery Simmons | DET | Right End | 21 | 1 | 4 | 27 | 0 | 0 | 0.0 | 0 |
| Randy Gregory | PHI | Right End | 21 | 1 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Aaron Donald | PHO | Right End | 19 | 0 | 8 | 69 | 0 | 0 | 0.0 | 0 |
| Nick Williams | LAC | Left End | 19 | 0 | 2 | 13 | 0 | 0 | 0.0 | 0 |
| Nate Hobbs | SCS | CB | 19 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| C. Gardner-Johnson | MIS | CB | 19 | 0 | 0 | 0 | 2 | 4 | 2.0 | 0 |
| Kyle Fuller | SF4 | CB | 19 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Chuck Clark | LAC | Strong Safety | 19 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Derek Barnett | SEA | Right End | 18 | 0 | 2 | 12 | 1 | 0 | 0.0 | 0 |
| Tarron Jackson | SF4 | Def End | 18 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| J.J. Watt | NYG | Def End | 18 | 0 | 0 | 0 | 1 | 76 | 76.0 | 1 |
| Rakeem Nunez-Roches | CAL | Def Tackle | 17 | 0 | 1 | 0 | 0 | 0 | 0.0 | 0 |
| Shelby Harris | CAL | Right End | 17 | 0 | 1 | 12 | 1 | 47 | 47.0 | 1 |
| Johnathan Hankins | CAL | Left Tackle | 17 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Taco Charlton | GBP | Def End | 17 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Chandon Sullivan | NOV | CB | 17 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Eric Stokes | DET | Left CB | 16 | 0 | 0 | 0 | 1 | 25 | 25.0 | 0 |
| Avonte Maddox | NYG | CB | 15 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Jourdan Lewis | BUF | CB | 15 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Deon Bush | SHR | Safety | 15 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Lawrence Guy | SF4 | Left End | 15 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Juan Thornhill | PHI | Free Safety | 15 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Stephon Gilmore | OAK | CB | 15 | 0 | 0 | 0 | 1 | 0 | 0.0 | 0 |
| Kyle Dugger | NOS | Strong Safety | 14 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Calais Campbell | BAC | Right End | 14 | 1 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Danny Johnson | CLE | CB | 14 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Cameron Heyward | SCS | Right End | 13 | 1 | 3 | 27 | 0 | 0 | 0.0 | 0 |
| Ross Cockrell | DAL | CB | 13 | 0 | 0 | 0 | 1 | 0 | 0.0 | 0 |
| Morgan Fox | LAD | Right End | 12 | 0 | 0 | 0 | 1 | 4 | 4.0 | 0 |
| Dont'e Deayon | LAM | CB | 12 | 0 | 0 | 0 | 1 | 0 | 0.0 | 0 |
| Nasir Adderley | LAD | Free Safety | 12 | 0 | 0 | 0 | 1 | 0 | 0.0 | 0 |
| Emmanuel Moseley | GBP | Left CB | 11 | 0 | 0 | 0 | 1 | 0 | 0.0 | 0 |
| Malik Reed | DAL | Left O LB | 11 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Mike Danna | LAC | Def End | 10 | 0 | 2 | 14 | 0 | 0 | 0.0 | 0 |
| Tavierre Thomas | PHO | CB | 10 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Marlon Humphrey | JAC | Right CB | 10 | 0 | 0 | 0 | 3 | 12 | 4.0 | 0 |
| Mike Hilton | BAC | CB | 10 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Chase Young | DAL | Left End | 10 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Duron Harmon | SEA | Free Safety | 10 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Ronald Darby | DET | Right CB | 9 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Alex Highsmith | DET | Right O LB | 8 | 0 | 4 | 34 | 0 | 0 | 0.0 | 0 |
| Malcolm Jenkins | CHI | Strong Safety | 8 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Rayshawn Jenkins | TTR | Strong Safety | 8 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Mario Addison | GBP | Def End | 6 | 0 | 3 | 20 | 0 | 0 | 0.0 | 0 |
| Keanu Neal | NOV | Middle LB | 6 | 1 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Travin Howard | BUF | I LB | 5 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Kyler Fackrell | LAD | O LB | 5 | 1 | 0 | 0 | 1 | 0 | 0.0 | 0 |
| Johnathan Abram | LAC | Strong Safety | 5 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Juston Burris | CAL | Safety | 5 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Arden Key | SF4 | Def End | 4 | 0 | 1 | 12 | 0 | 0 | 0.0 | 0 |
| Davon Godchaux | PHO | Nose Tackle | 4 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Armon Watts | MIS | Def Tackle | 3 | 0 | 3 | 23 | 0 | 0 | 0.0 | 0 |
| Malcom Brown | BUF | Nose Tackle | 3 | 0 | 1 | 0 | 0 | 0 | 0.0 | 0 |
| Ugo Amadi | NOV | 1st Defensive Back | 3 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Artie Burns | LAD | CB | 3 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Solomon Thomas | CAL | Def Tackle | 3 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Frank Clark | SF4 | Right End | 3 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Melvin Ingram III | LAM | Left End | 2 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Andrew Sendejo | BAC | Free Safety | 2 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Carlos Dunlap | SEA | Def End | 2 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Charvarius Ward | JAC | Left CB | 2 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| David Long Jr | SCS | 1st Defensive Back | 2 | 0 | 0 | 0 | 1 | 0 | 0.0 | 0 |
| Zach Sieler | PHO | Right End | 2 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Darious Williams | CLE | Right CB | 2 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Sidney Jones | NYG | Left CB | 2 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| K'Lavon Chaisson | CHI | Right O LB | 1 | 0 | 1 | 10 | 0 | 0 | 0.0 | 0 |
| Boogie Basham | BUF | Def End | 1 | 0 | 1 | 11 | 0 | 0 | 0.0 | 0 |
| Elijah Molden | SEA | CB | 1 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Kentavius Street | LAD | Def Tackle | 1 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Troy Reeder | CHI | Right I LB | 1 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Brandon Jones | CHI | Strong Safety | 1 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Justin Reid | BUF | Free Safety | 1 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Troy Hill | MIS | CB | 1 | 0 | 0 | 0 | 1 | 4 | 4.0 | 0 |
| Marcus Epps | SHR | Safety | 1 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0 |
| Sum | --- | --- | 16969 | 133 | 500 | 3452 | 316 | 3771 | 11.9 | 25 |
| Avg | --- | --- | 52 | 0 | 2 | 11 | 1 | 12 | 11.9 | 0 |